prikaz prve stranice dokumenta Clinical characteristics at presentation of type 1 diabetes mellitus in children younger than 15 years in Croatia
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Scientific paper - Original scientific paper
Clinical characteristics at presentation of type 1 diabetes mellitus in children younger than 15 years in Croatia
Journal of Pediatric Endocrinology and Metabolism, 24 (2011), 9-10; 655-670. https://doi.org/10.1515/JPEM.2011.231
Stipančić, Gordana; Požgaj Šepec, Marija; La Grasta Sabolić, Lavinija; Radica, Ana; Škrabić, Veselin; Severinski, Srećko; Kujundžic Tiljak, Mirjana

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Stipančić, G., Požgaj Šepec, M., La Grasta Sabolić, L., Radica, A., Škrabić, V., Severinski, S. & Kujundžic Tiljak, M. (2011). Clinical characteristics at presentation of type 1 diabetes mellitus in children younger than 15 years in Croatia. Journal of Pediatric Endocrinology and Metabolism, 24. (9-10), 655-670. doi: 10.1515/JPEM.2011.231

Stipančić, Gordana, et al. "Clinical characteristics at presentation of type 1 diabetes mellitus in children younger than 15 years in Croatia." Journal of Pediatric Endocrinology and Metabolism, vol. 24, no. 9-10, 2011, pp. 655-670. https://doi.org/10.1515/JPEM.2011.231

Stipančić, Gordana, Marija Požgaj Šepec, Lavinija La Grasta Sabolić, Ana Radica, Veselin Škrabić, Srećko Severinski and Mirjana Kujundžic Tiljak. "Clinical characteristics at presentation of type 1 diabetes mellitus in children younger than 15 years in Croatia." Journal of Pediatric Endocrinology and Metabolism 24, no. 9-10 (2011): 655-670. https://doi.org/10.1515/JPEM.2011.231

Stipančić, G., et al. (2011) 'Clinical characteristics at presentation of type 1 diabetes mellitus in children younger than 15 years in Croatia', Journal of Pediatric Endocrinology and Metabolism, 24(9-10), pp. 655-670. doi: 10.1515/JPEM.2011.231

Stipančić G, Požgaj Šepec M, La Grasta Sabolić L, Radica A, Škrabić V, Severinski S, and sur.. Clinical characteristics at presentation of type 1 diabetes mellitus in children younger than 15 years in Croatia. Journal of Pediatric Endocrinology and Metabolism [Internet]. 2011 [cited 2024 November 16];24(9-10):655-670. doi: 10.1515/JPEM.2011.231

G. Stipančić, et al., "Clinical characteristics at presentation of type 1 diabetes mellitus in children younger than 15 years in Croatia", Journal of Pediatric Endocrinology and Metabolism, vol. 24, no. 9-10, pp. 655-670, 2011. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:220:713663. [Accessed: 16 November 2024]

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Metadata
Title (english)Clinical characteristics at presentation of type 1 diabetes mellitus in children younger than 15 years in Croatia
AuthorGordana Stipančić
AuthorMarija Požgaj Šepec
AuthorLavinija La Grasta Sabolić
AuthorAna Radica
AuthorVeselin Škrabić
AuthorSrećko Severinski
AuthorMirjana Kujundžic Tiljak
Author's institution(Sestre milosrdnice University Hospital Center)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pediatrics
Abstract (english)
The aim of the study was to determine the clinical and biochemical characteristics of type 1 diabetes mellitus (DM) at presentation in children younger than 15 years in Croatia during a 9-year period, with special attention to diabetic ketoacidosis (DKA) incidence. The registered data set comprised blood glucose, pH, serum bicarbonate levels, and clinical symptoms at disease manifestation. During the study period, 692 children were diagnosed with type 1 DM. Polydipsia (96.7 % ), polyuria (96.05 % ), and weight loss (82.7 % ) were the most frequent symptoms anticipating disease detection. Enuresis was recorded in 11.55 % . A total of 36.41 % patients had DKA (pH < 7.3) at disease onset. During the 9-year period, the percentage of children presenting with DKA at time of diagnosis decreased from 41.67 % to 33.33 % (z = 1.68, p = 0.046). A positive family history of DM, the only factor with an impact on the DKA incidence rate in our population, lowers the probability of the development of ketoacidosis. This study confirms the importance of the detection of the classic symptoms of polyuria, polydipsia, and weight loss in patients with new-onset type 1 DM. The percentage of patients with DKA at diabetes onset decreased during the observed period but is still high and includes one-third of all patients. This is why in every acutely ill child, especially at a younger age, one should evaluate the possibility of type 1 DM to avoid the development of ketoacidosis.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleJournal of Pediatric Endocrinology and Metabolism
Numberingvol. 24, no. 9-10, pp. 655-670
p-ISSN0334-018X
e-ISSN2191-0251
DOIhttps://doi.org/10.1515/JPEM.2011.231
URN:NBNurn:nbn:hr:220:713663
Publication2011
Document URLhttps://www.degruyter.com/document/doi/10.1515/JPEM.2011.231/html
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2024-01-15 09:57:50