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Professional paper - Review paper
The Risk of Hypercoagulability in Ovarian Hyperstimulation Syndrome
Acta clinica Croatica, 54 (2015), 2; 186-192. urn:nbn:hr:220:373984
Danolić, Damir; Kasum, Miro; Puljiz, Mario; Alvir, Ilija; Tomica, Darko; Mamić, Ivica; Čehić, Ermin; Bolanča, Ivan

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Danolić, D., Kasum, M., Puljiz, M., Alvir, I., Tomica, D., Mamić, I. ... Bolanča, I. (2015). The Risk of Hypercoagulability in Ovarian Hyperstimulation Syndrome. Acta clinica Croatica, 54. (2), 186-192. Retrieved from https://urn.nsk.hr/urn:nbn:hr:220:373984

Danolić, Damir, et al. "The Risk of Hypercoagulability in Ovarian Hyperstimulation Syndrome." Acta clinica Croatica, vol. 54, no. 2, 2015, pp. 186-192. https://urn.nsk.hr/urn:nbn:hr:220:373984

Danolić, Damir, Miro Kasum, Mario Puljiz, Ilija Alvir, Darko Tomica, Ivica Mamić, Ermin Čehić and Ivan Bolanča. "The Risk of Hypercoagulability in Ovarian Hyperstimulation Syndrome." Acta clinica Croatica 54, no. 2 (2015): 186-192. https://urn.nsk.hr/urn:nbn:hr:220:373984

Danolić, D., et al. (2015) 'The Risk of Hypercoagulability in Ovarian Hyperstimulation Syndrome', Acta clinica Croatica, 54(2), pp. 186-192. Available at: https://urn.nsk.hr/urn:nbn:hr:220:373984 (Accessed 22 January 2025)

Danolić D, Kasum M, Puljiz M, Alvir I, Tomica D, Mamić I, and sur.. The Risk of Hypercoagulability in Ovarian Hyperstimulation Syndrome. Acta clinica Croatica [Internet]. 2015 [cited 2025 January 22];54(2):186-192. Available at: https://urn.nsk.hr/urn:nbn:hr:220:373984

D. Danolić, et al., "The Risk of Hypercoagulability in Ovarian Hyperstimulation Syndrome", Acta clinica Croatica, vol. 54, no. 2, pp. 186-192, 2015. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:220:373984. [Accessed: 22 January 2025]

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Metadata
Title (english)The Risk of Hypercoagulability in Ovarian Hyperstimulation Syndrome
Title (croatian)Rizik hiperkoagulabilnosti kod sindromahiperstimulacije jajnika
AuthorDamir Danolić
AuthorMiro Kasum
AuthorMario Puljiz
AuthorIlija Alvir
AuthorDarko Tomica
AuthorIvica Mamić
AuthorErmin Čehić
AuthorIvan Bolanča
Author's institution(Sestre milosrdnice University Hospital Center)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Gynecology and Obstetrics
Abstract (english)
Ovarian hyperstimulation syndrome (OHSS) is a rare and potentially life-threatening complication of infertility treatment occurring during either the luteal phase or early pregnancy. An increasing number of thromboembolic complications associated with the increased use of assisted reproductive techniques have been reported in the literature. Identification of the risk factors is crucial for prevention of thromboembolic events in OHSS patients. Alterations in the hemostatic system cause hypercoagulability in women affected by severe OHSS. Coexistence of inherited hypercoagulable conditions increases the risk of thromboembolism. The role of clinical parameters that can help predict development of thrombosis is controversial. Patients with a personal or family history of thrombosis undergoing infertility treatment should be considered for thrombophilia screening, while routine examination of inherited thrombophilic mutations is not indicated in infertile patients. Antithrombotic primary prevention is not indicated in healthy women undergoing assisted reproductive procedures or in women with thrombophilia. Anticoagulant therapy is indicted if there is clinical evidence of thrombosis or laboratory evidence of hypercoagulability. In this review, the risks of hypercoagulability in the OHSS are discussed.
Abstract (croatian)
Sindrom hiperstimulacije jajnika je rijetka i za život opasna komplikacija liječenja neplodnosti koja se javlja u lutealnoj fazi menstruacijskog ciklusa ili tijekom rane trudnoće. Povećanjem zastupljenosti tehnika potpomognute oplodnje povećava se broj prijavljenih slučajeva tromboembolijskih komplikacija. U prevenciji tromboembolijskih događaja kod bolesnica sa sindromom hiperstimulacije jajnika ključno je određivanje rizičnih čimbenika. Promjene u sustavu hemostaze uzrokuju hipekoagulabilnost, a nasljedne trombofilije dodatno povećavaju rizik tromboembolije. Sporna je uloga kliničkih parametara koji mogu pomoći u predviđanju razvoja tromboze. Žene podvrgnute liječenju neplodnosti koje su preboljele tromboembolijsku bolest ili u obitelji imaju slučajeve tromboembolijske bolesti treba testirati na nasljedne trombofilije, dok se rutinsko testiranje kod neplodnih žena ne provodi. Antitrombotska terapija je indicirana samo ako su prisutni klinički znakovi tromboze ili laboratorijski dokazana hiperkoagulabilnost, a nije indicirana kod žena s nasljednom trombofilijom u postupku medicinski potpomognute oplodnje bez kliničkih i/ili laboratorijskih znakova tromboze. U ovom preglednom članku opisani su rizici hiperkoagulabilnosti u sindromu hiperstimulacije jajnika.
Keywords (english)
Keywords (croatian)
Languageenglish
Languagecroatian
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleActa clinica Croatica
Numberingvol. 54, no. 2, pp. 186-192
p-ISSN0353-9466
e-ISSN1333-9451
URN:NBNurn:nbn:hr:220:373984
Publication2015
Document URLhttps://hrcak.srce.hr/145479
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2024-06-10 09:36:22