prikaz prve stranice dokumenta Urinary troponin concentration as a marker of cardiac damage in pregnancies complicated with preeclampsia
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Urinary troponin concentration as a marker of cardiac damage in pregnancies complicated with preeclampsia
Medical Hypotheses, 144 (2020); 110252. https://doi.org/10.1016/j.mehy.2020.110252
Potkonjak, Ana Meyra; Sabolović Rudman, Senka; Nikolac Gabaj, Nora; Kuna, Krunoslav; Košec, Vesna; Stanec, Zdenko; Zovak, Mario; Tučkar, Neven; Djaković, Ivka; Prkačin, Ingrid; Svaguša, Tomo; Bakoš, Matija

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Potkonjak, A. M., Sabolović Rudman, S., Nikolac Gabaj, N., Kuna, K., Košec, V., Stanec, Z. ... Bakoš, M. (2020). Urinary troponin concentration as a marker of cardiac damage in pregnancies complicated with preeclampsia. Medical Hypotheses, 144.. doi: 10.1016/j.mehy.2020.110252

Potkonjak, Ana Meyra, et al. "Urinary troponin concentration as a marker of cardiac damage in pregnancies complicated with preeclampsia." Medical Hypotheses, vol. 144, 2020. https://doi.org/10.1016/j.mehy.2020.110252

Potkonjak, Ana Meyra, Senka Sabolović Rudman, Nora Nikolac Gabaj, Krunoslav Kuna, Vesna Košec, Zdenko Stanec, Mario Zovak, et al. "Urinary troponin concentration as a marker of cardiac damage in pregnancies complicated with preeclampsia." Medical Hypotheses 144 (2020). https://doi.org/10.1016/j.mehy.2020.110252

Potkonjak, A. M., et al. (2020) 'Urinary troponin concentration as a marker of cardiac damage in pregnancies complicated with preeclampsia', Medical Hypotheses, 144. doi: 10.1016/j.mehy.2020.110252

Potkonjak AM, Sabolović Rudman S, Nikolac Gabaj N, Kuna K, Košec V, Stanec Z, and sur.. Urinary troponin concentration as a marker of cardiac damage in pregnancies complicated with preeclampsia. Medical Hypotheses [Internet]. 2020 November [cited 2024 December 08];144. doi: 10.1016/j.mehy.2020.110252

A. M. Potkonjak, et al., "Urinary troponin concentration as a marker of cardiac damage in pregnancies complicated with preeclampsia", Medical Hypotheses, vol. 144, November 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:220:525078. [Accessed: 08 December 2024]

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Metadata
Title (english)Urinary troponin concentration as a marker of cardiac damage in pregnancies complicated with preeclampsia
AuthorAna Meyra Potkonjak
AuthorSenka Sabolović Rudman
AuthorNora Nikolac Gabaj
AuthorKrunoslav Kuna
AuthorVesna Košec
AuthorZdenko Stanec
AuthorMario Zovak
AuthorNeven Tučkar
AuthorIvka Djaković
AuthorIngrid Prkačin
AuthorTomo Svaguša
AuthorMatija Bakoš
Author's institution(Sestre milosrdnice University Hospital Center)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Pregnant women with preeclampsia experience significant hemodynamic changes which lead to an increased myocardial workload. In response to increased demands in pregnancy, the heart muscle responds with ventricular remodeling process which involves cardiac muscle hypertrophy. Opposed to occurrence of eccentric ventricular hypertrophy in normal pregnancy, myocardial remodeling in a form of concentric hypertrophy will occur in pregnant patients with preeclampsia. Increased myocardial workload is manifested by an increased troponin release. As process of troponin degradation continue, filtration of degradation fragment through glomerular membrane occur, raising the possibility of it's detection in urine. Degradation fragments of troponin molecules are estimated to be 20 kDa with preserved immunoreactivity to high-sensitivity assays. Some of the authors suggest that serum levels of cardiac troponin I might be elevated in patients with hypertension, as well as in preeclamptic pregnant women. It is to be expected that evaluation of severity of the myocardial damage in pregnant woman with preeclampsia may be performed by measuring levels of troponin in the urine using high-sensitivity assays. Designing of urine dipstick will help to detect an early phase of myocardial involvement in preeclamptic pregnancies.
Keywords (english)
Languageenglish
Publication typeProfessional paper - Other
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedical Hypotheses
Numberingvol. 144, 110252
p-ISSN0306-9877
DOIhttps://doi.org/10.1016/j.mehy.2020.110252
URN:NBNurn:nbn:hr:220:525078
Publication2020-11
Document URLhttps://linkinghub.elsevier.com/retrieve/pii/S0306987720318867
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2024-10-18 11:19:01