prikaz prve stranice dokumenta Laser biomodulation: application of the gallium - arsenide laser in cell growth modulation and in the treatment of ulcus cruris
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Scientific paper - Original scientific paper
Laser biomodulation: application of the gallium - arsenide laser in cell growth modulation and in the treatment of ulcus cruris
Medical science research, 27 (1999), 11; 775-778. urn:nbn:hr:220:850285
Žarković, Neven; Gulin, Marijana; Tršinski, Mladen; Cingulin, Velimir; Skala, Karolj; Tonković, Gordana; Škorić, Tanja; Stipančić, Igor; Sabolović, Senka; Soldo, Ivo

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Žarković, N., Gulin, M., Tršinski, M., Cingulin, V., Skala, K., Tonković, G. ... Soldo, I. (1999). Laser biomodulation: application of the gallium - arsenide laser in cell growth modulation and in the treatment of ulcus cruris. Medical science research, 27. (11), 775-778. Retrieved from https://urn.nsk.hr/urn:nbn:hr:220:850285

Žarković, Neven, et al. "Laser biomodulation: application of the gallium - arsenide laser in cell growth modulation and in the treatment of ulcus cruris." Medical science research, vol. 27, no. 11, 1999, pp. 775-778. https://urn.nsk.hr/urn:nbn:hr:220:850285

Žarković, Neven, Marijana Gulin, Mladen Tršinski, Velimir Cingulin, Karolj Skala, Gordana Tonković, Tanja Škorić, Igor Stipančić, Senka Sabolović and Ivo Soldo. "Laser biomodulation: application of the gallium - arsenide laser in cell growth modulation and in the treatment of ulcus cruris." Medical science research 27, no. 11 (1999): 775-778. https://urn.nsk.hr/urn:nbn:hr:220:850285

Žarković, N., et al. (1999) 'Laser biomodulation: application of the gallium - arsenide laser in cell growth modulation and in the treatment of ulcus cruris', Medical science research, 27(11), pp. 775-778. Available at: https://urn.nsk.hr/urn:nbn:hr:220:850285 (Accessed 22 November 2024)

Žarković N, Gulin M, Tršinski M, Cingulin V, Skala K, Tonković G, and sur.. Laser biomodulation: application of the gallium - arsenide laser in cell growth modulation and in the treatment of ulcus cruris. Medical science research [Internet]. 1999 [cited 2024 November 22];27(11):775-778. Available at: https://urn.nsk.hr/urn:nbn:hr:220:850285

N. Žarković, et al., "Laser biomodulation: application of the gallium - arsenide laser in cell growth modulation and in the treatment of ulcus cruris", Medical science research, vol. 27, no. 11, pp. 775-778, 1999. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:220:850285. [Accessed: 22 November 2024]

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Metadata
Title (english)Laser biomodulation: application of the gallium - arsenide laser in cell growth modulation and in the treatment of ulcus cruris
AuthorNeven Žarković
AuthorMarijana Gulin
AuthorMladen Tršinski
AuthorVelimir Cingulin
AuthorKarolj Skala
AuthorGordana Tonković
AuthorTanja Škorić
AuthorIgor Stipančić
AuthorSenka Sabolović
AuthorIvo Soldo
Author's institution(Sestre milosrdnice University Hospital Center)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The aim of this study was to test the hypothesis that exposure to low-power laser energy can modulate cell growth and differentiation under certain physiological conditions. Specifically, this hypothesis predicts that in conditions of rapid cycling (e.g. in vitro cell proliferation and in vivo wound healing in mice), laser treatment will have little or no stimulating effect on the rate of cell proliferation and might even inhibit cell growth. However, in conditions of slow cycling (e.g. healing of ulcus cruris) laser treatment will stimulate cell proliferation. To test the hypothesis, we evaluated the effect of exposure to a pulsed GaAs semi-conductor laser (50 W peak power, 904 nm wavelength at energy density of 1.05 J/cm®) on the proliferation of L.929 fibroblasts cell cultures, the healing of murine skin wounds and on the healing of human leg ulcers. Lasing did not stimulate the growth of cultured fibroblasts, nor the healing of skin wounds in mice. It did, however, promote healing of skin ulcers in 34 out of 40 patients evaluated. These data support the principle of cellular modulation by laser treatment and indicate that such biomodulation may have a therapeutic application in the treatment of ulcus cruris.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewUnknown
Publication versionPublished version
Journal titleMedical science research
Numberingvol. 27, no. 11, pp. 775-778
p-ISSN0269-8951
URN:NBNurn:nbn:hr:220:850285
Publication1999
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2024-10-18 12:39:01