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Scientific paper - Review paper
The Use of Electroretinography and Optical Coherence Tomography in Patients with Schizophrenia
Acta clinica Croatica, 59 (2020), 4; 729-739. https://doi.org/10.20471/acc.2020.59.04.20
Duraković, Din; Silić, Ante; Peitl, Vjekoslav; Tadić, Rašeljka; Lončarić, Kristina; Glavina, Trpimir; Šago, Daniela; Pačić Turk, Ljiljana; Karlović, Dalibor

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Duraković, D., Silić, A., Peitl, V., Tadić, R., Lončarić, K., Glavina, T. ... Karlović, D. (2020). The Use of Electroretinography and Optical Coherence Tomography in Patients with Schizophrenia. Acta clinica Croatica, 59. (4), 729-739. doi: 10.20471/acc.2020.59.04.20

Duraković, Din, et al. "The Use of Electroretinography and Optical Coherence Tomography in Patients with Schizophrenia." Acta clinica Croatica, vol. 59, no. 4, 2020, pp. 729-739. https://doi.org/10.20471/acc.2020.59.04.20

Duraković, Din, Ante Silić, Vjekoslav Peitl, Rašeljka Tadić, Kristina Lončarić, Trpimir Glavina, Daniela Šago, Ljiljana Pačić Turk and Dalibor Karlović. "The Use of Electroretinography and Optical Coherence Tomography in Patients with Schizophrenia." Acta clinica Croatica 59, no. 4 (2020): 729-739. https://doi.org/10.20471/acc.2020.59.04.20

Duraković, D., et al. (2020) 'The Use of Electroretinography and Optical Coherence Tomography in Patients with Schizophrenia', Acta clinica Croatica, 59(4), pp. 729-739. doi: 10.20471/acc.2020.59.04.20

Duraković D, Silić A, Peitl V, Tadić R, Lončarić K, Glavina T, and sur.. The Use of Electroretinography and Optical Coherence Tomography in Patients with Schizophrenia. Acta clinica Croatica [Internet]. 2020 [cited 2024 December 07];59(4):729-739. doi: 10.20471/acc.2020.59.04.20

D. Duraković, et al., "The Use of Electroretinography and Optical Coherence Tomography in Patients with Schizophrenia", Acta clinica Croatica, vol. 59, no. 4, pp. 729-739, 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:220:294712. [Accessed: 07 December 2024]

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Metadata
Title (english)The Use of Electroretinography and Optical Coherence Tomography in Patients with Schizophrenia
Title (croatian)Primjena elektroretinografije i optičke koherentne tomografije u bolesnika sa shizofrenijom
AuthorDin Duraković
AuthorAnte Silić
AuthorVjekoslav Peitl
AuthorRašeljka Tadić
AuthorKristina Lončarić
AuthorTrpimir Glavina
AuthorDaniela Šago
AuthorLjiljana Pačić Turk
AuthorDalibor Karlović
Author's institution(Sestre milosrdnice University Hospital Center)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
The use of electroretinography (ERG) and optical coherence tomography (OCT) has currently expanded beyond ophthalmology alone. The aim of this review is to present the results and knowledge acquired by these two methods in patients suffering from schizophrenia. Reviewing the studies applying ERG and OCT methods in the field of psychiatry, one can conclude that results of the research imply morphological and functional changes of retina in patients with schizophrenia that are not consistent. However, in most studies there was reduction of the amplitude and changes in the implicit time related parameters on ERG and thinning of the retinal nerve fiber layer on OCT. Neurons in the eye use the same neurotransmitters as neurons in the basal brain structures that are most affected in schizophrenia, according to the dopamine hypothesis of schizophrenia. Unlike neurons in the basal brain structures, the neurons in the eye are in vivo available to ERG. Using the aforementioned tests together with clinical diagnostic criteria of schizophrenia, the subgroups with different prognostic and therapeutic specificities within schizophrenia as a group of diseases might be identified more precisely.
Abstract (croatian)
Primjena elektroretinografije (ERG) i optičke koherentne tomografije (OCT) danas nadilazi primjenu isključivo u oftalmologiji. Cilj ovoga pregleda je prikazati rezultate i spoznaje dobivene primjenom ovih metoda u shizofrenih bolesnika. Pregledom dosadašnjih istraživanja primjene metoda ERG-a i OCT-a u području psihijatrije možemo zaključiti da rezultati provedenih istraživanja morfoloških i funkcionalnih promjena retine u bolesnika sa shizofrenijom nisu konzistentni. Ipak, u većini istraživanja nalaze se smanjenje amplituda i promjene implicitnog vremena u ERG-u te stanjenje sloja mrežničnih živčanih vlakana na OCT-u. Kako se radi o neuronima dostupnima in vivo koji koriste iste neurotransmitere kao i neuroni u središnjim strukturama mozga koji su po dopaminskoj hipotezi shizofrenije najzahvaćeniji, primjenom spomenutih pretraga uz uobičajenu dijagnostiku shizofrenije možemo očekivati definiranje jasnijih podskupina unutar shizofrenije kao skupine bolesti koje bi imale različite prognostičke i terapijske specifičnosti.
Keywords (english)
Keywords (croatian)
Languageenglish
Languagecroatian
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleActa clinica Croatica
Numberingvol. 59, no. 4, pp. 729-739
p-ISSN0353-9466
e-ISSN1333-9451
DOIhttps://doi.org/10.20471/acc.2020.59.04.20
URN:NBNurn:nbn:hr:220:294712
Publication2020
Document URLhttps://hrcak.srce.hr/254898
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-10-22 10:33:01