prikaz prve stranice dokumenta Transient clitoromegaly in an extremely preterm twin infant with popliteal pterygium
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Scientific paper - Case study
Transient clitoromegaly in an extremely preterm twin infant with popliteal pterygium
Pediatric Endocrinology Diabetes and Metabolism, 30 (2024), 3; 163-167. https://doi.org/10.5114/pedm.2024.142585
La Grasta Sabolić, Lavinia; Kovačević, Ana; Trtanj, Lucija Ana; Valent Morić, Bernardica; Tumbri, Jasna

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La Grasta Sabolić, L., Kovačević, A., Trtanj, L. A., Valent Morić, B. & Tumbri, J. (2024). Transient clitoromegaly in an extremely preterm twin infant with popliteal pterygium. Pediatric Endocrinology Diabetes and Metabolism, 30. (3), 163-167. doi: 10.5114/pedm.2024.142585

La Grasta Sabolić, Lavinia, et al. "Transient clitoromegaly in an extremely preterm twin infant with popliteal pterygium." Pediatric Endocrinology Diabetes and Metabolism, vol. 30, no. 3, 2024, pp. 163-167. https://doi.org/10.5114/pedm.2024.142585

La Grasta Sabolić, Lavinia, Ana Kovačević, Lucija Ana Trtanj, Bernardica Valent Morić and Jasna Tumbri. "Transient clitoromegaly in an extremely preterm twin infant with popliteal pterygium." Pediatric Endocrinology Diabetes and Metabolism 30, no. 3 (2024): 163-167. https://doi.org/10.5114/pedm.2024.142585

La Grasta Sabolić, L., et al. (2024) 'Transient clitoromegaly in an extremely preterm twin infant with popliteal pterygium', Pediatric Endocrinology Diabetes and Metabolism, 30(3), pp. 163-167. doi: 10.5114/pedm.2024.142585

La Grasta Sabolić L, Kovačević A, Trtanj LA, Valent Morić B, Tumbri J. Transient clitoromegaly in an extremely preterm twin infant with popliteal pterygium. Pediatric Endocrinology Diabetes and Metabolism [Internet]. 2024 [cited 2024 November 20];30(3):163-167. doi: 10.5114/pedm.2024.142585

L. La Grasta Sabolić, A. Kovačević, L. A. Trtanj, B. Valent Morić and J. Tumbri, "Transient clitoromegaly in an extremely preterm twin infant with popliteal pterygium", Pediatric Endocrinology Diabetes and Metabolism, vol. 30, no. 3, pp. 163-167, 2024. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:220:926457. [Accessed: 20 November 2024]

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Metadata
Title (english)Transient clitoromegaly in an extremely preterm twin infant with popliteal pterygium
AuthorLavinia La Grasta Sabolić
AuthorAna Kovačević
AuthorLucija Ana Trtanj
AuthorBernardica Valent Morić
AuthorJasna Tumbri
Author's institution(Sestre milosrdnice University Hospital Center)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Clitoromegaly can be congenital or acquired, and it is usually associated with exposure to androgen excess. Pathophysiological mechanisms responsible for transient clitoromegaly in premature female infants have not been fully elucidated. Herein, we present the case of an extremely premature female twin infant, with an extensive web of skin on the back of the left leg, hypoplastic left labia majora, and normal clitoris appearance at birth. At the age of 48 days, clitoral enlargement was observed. Significantly elevated levels of gonadotropins, testosterone, and dehydroepiandrosterone sulphate (DHEAS) were recorded. 17-hydroxyprogesterone (17OHP) was unremarkable, and anti-Müllerian hormone (AMH) was low, in accordance with normal female karyotype. Ovaries were not visualised ultrasonographically. During the following weeks, gradual normalisation of gonadotropin, testosterone, and DHEAS levels was accompanied by regression of clitoromegaly. As described in this case, transient clitoral enlargement may appear in extremely premature female infants due to transitory elevated androgens of ovarian and adrenal origin.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titlePediatric Endocrinology Diabetes and Metabolism
Numberingvol. 30, no. 3, pp. 163-167
p-ISSN2081-237X
DOIhttps://doi.org/10.5114/pedm.2024.142585
URN:NBNurn:nbn:hr:220:926457
Publication2024
Document URLhttps://www.termedia.pl/doi/10.5114/pedm.2024.142585
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-11-05 11:08:54