prikaz prve stranice dokumenta Is vitamin D associated with disease activity in patients with axial or peripheral spondyloarthritis? A real-life study
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Scientific paper - Original scientific paper
Is vitamin D associated with disease activity in patients with axial or peripheral spondyloarthritis? A real-life study
Rheumatology International, 44 (2024), 10; 2079-2087. https://doi.org/10.1007/s00296-024-05674-6
Mbuyi, Mirna Kalombo; Skala Kavangh, Hana; Grubišić, Frane; Doko Vajdić, Ines; Grazio, Simeon

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Mbuyi, M. K., Skala Kavangh, H., Grubišić, F., Doko Vajdić, I. & Grazio, S. (2024). Is vitamin D associated with disease activity in patients with axial or peripheral spondyloarthritis? A real-life study. Rheumatology International, 44. (10), 2079-2087. doi: 10.1007/s00296-024-05674-6

Mbuyi, Mirna Kalombo, et al. "Is vitamin D associated with disease activity in patients with axial or peripheral spondyloarthritis? A real-life study." Rheumatology International, vol. 44, no. 10, 2024, pp. 2079-2087. https://doi.org/10.1007/s00296-024-05674-6

Mbuyi, Mirna Kalombo, Hana Skala Kavangh, Frane Grubišić, Ines Doko Vajdić and Simeon Grazio. "Is vitamin D associated with disease activity in patients with axial or peripheral spondyloarthritis? A real-life study." Rheumatology International 44, no. 10 (2024): 2079-2087. https://doi.org/10.1007/s00296-024-05674-6

Mbuyi, M. K., et al. (2024) 'Is vitamin D associated with disease activity in patients with axial or peripheral spondyloarthritis? A real-life study', Rheumatology International, 44(10), pp. 2079-2087. doi: 10.1007/s00296-024-05674-6

Mbuyi MK, Skala Kavangh H, Grubišić F, Doko Vajdić I, Grazio S. Is vitamin D associated with disease activity in patients with axial or peripheral spondyloarthritis? A real-life study. Rheumatology International [Internet]. 2024 August 24 [cited 2024 December 12];44(10):2079-2087. doi: 10.1007/s00296-024-05674-6

M. K. Mbuyi, H. Skala Kavangh, F. Grubišić, I. Doko Vajdić and S. Grazio, "Is vitamin D associated with disease activity in patients with axial or peripheral spondyloarthritis? A real-life study", Rheumatology International, vol. 44, no. 10, pp. 2079-2087, August 2024. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:220:205476. [Accessed: 12 December 2024]

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Metadata
Title (english)Is vitamin D associated with disease activity in patients with axial or peripheral spondyloarthritis? A real-life study
AuthorMirna Kalombo Mbuyi
AuthorHana Skala Kavangh
AuthorFrane Grubišić
AuthorInes Doko Vajdić
AuthorSimeon Grazio
Author's institution(Sestre milosrdnice University Hospital Center)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Vitamin D plays important role in inflammatory rheumatic diseases, which in turn rose an interest for investigating association of its deficiency with disease activity. In this research we aimed to evaluate this matter in the context of spondyloarthritis (SpA), together with treatment modalities and bone density in people diagnosed with axial or peripheral SpA in real-life setting. In our study we enrolled 99 patients with diagnosis of SpA treated at the tertiary level rheumatology department. Serum 25(OH)D levels, treatment modality (NSAIR or DMARDs), disease activity, tobacco smoking habits, mineral density of bone, supplementation and seasonal variations were assessed. We used standardized questionnaires such as ASDAS-CRP, BASFI and joint count, among many others, to evaluate some of the mentioned parameters. Sixty-five percent of patients had vitamin D deficiency. We found marginaly higher activity of disease in subjects with low vitamin D. In cases of peripheral SpA, there was a significant association of higher number of swollen joints and lower vitamin D levels. Additionally, the significant correlation was seen between normal serum vitamin D and supplementation. In our real-life study of patients with SpA we found a significant percentage of vitamin D deficit, with a tendency of slightly higher disease activity in those patients.In order to clarify the impact of the vitamin on disease activity in SpA and the supplementation recommendations for patients with these conditions, the conduction of further studies is required.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleRheumatology International
Numberingvol. 44, no. 10, pp. 2079-2087
e-ISSN1437-160X
DOIhttps://doi.org/10.1007/s00296-024-05674-6
URN:NBNurn:nbn:hr:220:205476
Publication2024-08-24
Document URLhttps://link.springer.com/10.1007/s00296-024-05674-6
Type of resourceText
Access conditionsInstitutional access
Terms of useLicence In copyright icon
Created on2024-12-06 12:12:53