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Scientific paper - Case study
Interference of M-protein on Thrombin Time Test: A Case Report
Laboratory Medicine, 51 (2020), 5; 545-549. https://doi.org/10.1093/labmed/lmz103
Njegovan, Milena; Margetić, Sandra; Tešija Kuna, Andrea; Đerek, Lovorka; Ćelap, Ivana; Pavičić, Tomislav; Čaržavec, Dubravka; Gaćina, Petar

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Njegovan, M., Margetić, S., Tešija Kuna, A., Đerek, L., Ćelap, I., Pavičić, T. ... Gaćina, P. (2020). Interference of M-protein on Thrombin Time Test: A Case Report. Laboratory Medicine, 51. (5), 545-549. doi: 10.1093/labmed/lmz103

Njegovan, Milena, et al. "Interference of M-protein on Thrombin Time Test: A Case Report." Laboratory Medicine, vol. 51, no. 5, 2020, pp. 545-549. https://doi.org/10.1093/labmed/lmz103

Njegovan, Milena, Sandra Margetić, Andrea Tešija Kuna, Lovorka Đerek, Ivana Ćelap, Tomislav Pavičić, Dubravka Čaržavec and Petar Gaćina. "Interference of M-protein on Thrombin Time Test: A Case Report." Laboratory Medicine 51, no. 5 (2020): 545-549. https://doi.org/10.1093/labmed/lmz103

Njegovan, M., et al. (2020) 'Interference of M-protein on Thrombin Time Test: A Case Report', Laboratory Medicine, 51(5), pp. 545-549. doi: 10.1093/labmed/lmz103

Njegovan M, Margetić S, Tešija Kuna A, Đerek L, Ćelap I, Pavičić T, and sur.. Interference of M-protein on Thrombin Time Test: A Case Report. Laboratory Medicine [Internet]. 2020 [cited 2024 November 16];51(5):545-549. doi: 10.1093/labmed/lmz103

M. Njegovan, et al., "Interference of M-protein on Thrombin Time Test: A Case Report", Laboratory Medicine, vol. 51, no. 5, pp. 545-549, 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:220:385781. [Accessed: 16 November 2024]

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Metadata
Title (english)Interference of M-protein on Thrombin Time Test: A Case Report
AuthorMilena Njegovan
AuthorSandra Margetić
AuthorAndrea Tešija Kuna
AuthorLovorka Đerek
AuthorIvana Ćelap
AuthorTomislav Pavičić
AuthorDubravka Čaržavec
AuthorPetar Gaćina
Author's institution(Sestre milosrdnice University Hospital Center)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Objective: A case of interference of monoclonal protein (M-protein) on thrombin time (TT) test in a 39-year-old Caucasian male patient is presented. Methods: Coagulation screening tests were performed where altered results only for TT result (>150 seconds) and activated partial thromboplastin time (aPTT) result (36 seconds) were measured. Further specific coagulation testing included measurement of individual coagulation factors FII, FV, FVII, FVIII, FIX, FX, FXI, and FXII. Diagnostic steps in detection and identification of monoclonal protein included serum protein electrophoresis and immunofixation (both serum and urine specimen). Results: Monoclonal protein immunoglobulin G kappa detection and identification in serum and urine clarified the situation. Conclusion: Unexpectedly altered results of screening coagulation tests without any appropriate clinical signs and symptoms in a patient without any anticoagulant therapy needs to be critically considered in the context of extended next diagnostic steps in order to clarify the cause of pathological test results.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleLaboratory Medicine
Numberingvol. 51, no. 5, pp. 545-549
p-ISSN0007-5027
e-ISSN1943-7730
DOIhttps://doi.org/10.1093/labmed/lmz103
URN:NBNurn:nbn:hr:220:385781
Publication2020
Document URLhttps://academic.oup.com/labmed/article/51/5/545/5735480
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-09-09 11:43:46