prikaz prve stranice dokumenta Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience
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Scientific paper - Review paper
Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience
Collegium antropologicum, 35 (2011), 3; 957-962. urn:nbn:hr:220:483603
Tišlarić-Medenjak, Dubravka; Košec, Vesna; Tonković-Đurišević, Ivana; Zec, Ivana; Sabolović-Rudman, Senka; Kuna, Krunoslav; Herman, Radoslav; Ivičević-Bakulić, Tomislav; Soljačić-Vraneš, Hrvojka; Tučkar, Neven; Mužinić, Dubravka; Butorac, Dražan; Bolanča, Ivan; Košec, Andro; Stipoljev, Feodora More authors...

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Tišlarić Medenjak, D., Košec, V., Tonković Đurišević, I., Zec, I., Sabolović Rudman, S., Kuna, K. ... Stipoljev, F. (2011). Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience. Collegium antropologicum, 35. (3), 957-962. Retrieved from https://urn.nsk.hr/urn:nbn:hr:220:483603

Tišlarić Medenjak, Dubravka, et al. "Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience." Collegium antropologicum, vol. 35, no. 3, 2011, pp. 957-962. https://urn.nsk.hr/urn:nbn:hr:220:483603

Tišlarić Medenjak, Dubravka, Vesna Košec, Ivana Tonković Đurišević, Ivana Zec, Senka Sabolović Rudman, Krunoslav Kuna, Radoslav Herman, et al. "Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience." Collegium antropologicum 35, no. 3 (2011): 957-962. https://urn.nsk.hr/urn:nbn:hr:220:483603

Tišlarić Medenjak, D., et al. (2011) 'Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience', Collegium antropologicum, 35(3), pp. 957-962. Available at: https://urn.nsk.hr/urn:nbn:hr:220:483603 (Accessed 07 March 2025)

Tišlarić Medenjak D, Košec V, Tonković Đurišević I, Zec I, Sabolović Rudman S, Kuna K, and sur.. Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience. Collegium antropologicum [Internet]. 2011 [cited 2025 March 07];35(3):957-962. Available at: https://urn.nsk.hr/urn:nbn:hr:220:483603

D. Tišlarić Medenjak, et al., "Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience", Collegium antropologicum, vol. 35, no. 3, pp. 957-962, 2011. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:220:483603. [Accessed: 07 March 2025]

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Metadata
Title (english)Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience
AuthorDubravka Tišlarić-Medenjak
AuthorVesna Košec
AuthorIvana Tonković-Đurišević
AuthorIvana Zec
AuthorSenka Sabolović-Rudman
AuthorKrunoslav Kuna
AuthorRadoslav Herman
AuthorTomislav Ivičević-Bakulić
AuthorHrvojka Soljačić-Vraneš
AuthorNeven Tučkar
AuthorDubravka Mužinić
AuthorDražan Butorac
AuthorIvan Bolanča
AuthorAndro Košec
AuthorFeodora Stipoljev
Author's institution(Sestre milosrdnice University Hospital Center)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Gynecology and Obstetrics
Abstract (english)
The aim of the study is to investigate the efficiency of the second-trimester biochemical screening, with maternal serum alpha-fetoprotein (MS-AFP) and free b-subunit of human chorionic gonadotropin (free b-hCG), during the ten-year period. The study included 11,292 of pregnant women between the 15th and 18th gestational week, who underwent screening from November 1996 to December 2006. The risk for trisomy 21 and trisomy 18 were calculated by computer software, based on a model which generated the final risk for fetal aneuploidies from the pregnant woman’s a priori age risk and the likelihood ratio of the distribution of the biochemical markers, according to the second-trimester gestation. With the cut-off value of the final risk 1:250, the detection rate for trisomy 21 was 75% (21/28). In women less than or equal to 35, the detection was 57.1% (8/14) and 92.9% (13/14) in those over 35 years, respectively. The detection rate of trisomy 18 was 50% (2/4). The results confirmed that the implementation of double-test, as non-invasive screening for fetal aneuploidies, should be accepted as a complementary method of antenatal care.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleCollegium antropologicum
Numberingvol. 35, no. 3, pp. 957-962
p-ISSN0350-6134
e-ISSN1848-9486
URN:NBNurn:nbn:hr:220:483603
Publication2011
Document URLhttps://hrcak.srce.hr/72207
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-06-12 08:19:21