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Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience
Collegium antropologicum, 35 (2011), 3; 957-962. urn:nbn:hr:220:483603
Tišlarić-Medenjak, Dubravka; Košec, Vesna; Tonković-Đurišević, Ivana; Zec, Ivana; Sabolović-Rudman, Senka; Kuna, Krunoslav; Herman, Radoslav; Ivičević-Bakulić, Tomislav; Soljačić-Vraneš, Hrvojka; Tučkar, Neven; Mužinić, Dubravka; Butorac, Dražan; Bolanča, Ivan; Košec, Andro; Stipoljev, Feodora Više autora...

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Tišlarić Medenjak, D., Košec, V., Tonković Đurišević, I., Zec, I., Sabolović Rudman, S., Kuna, K. ... Stipoljev, F. (2011). Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience. Collegium antropologicum, 35. (3), 957-962. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:220:483603

Tišlarić Medenjak, Dubravka, et al. "Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience." Collegium antropologicum, vol. 35, br. 3, 2011, str. 957-962. https://urn.nsk.hr/urn:nbn:hr:220:483603

Tišlarić Medenjak, Dubravka, Vesna Košec, Ivana Tonković Đurišević, Ivana Zec, Senka Sabolović Rudman, Krunoslav Kuna, Radoslav Herman, et al. "Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience." Collegium antropologicum 35, br. 3 (2011): 957-962. https://urn.nsk.hr/urn:nbn:hr:220:483603

Tišlarić Medenjak, D., et al. (2011) 'Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience', Collegium antropologicum, 35(3), str. 957-962. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:220:483603 (Datum pristupa: 08.12.2024.)

Tišlarić Medenjak D, Košec V, Tonković Đurišević I, Zec I, Sabolović Rudman S, Kuna K, i sur.. Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience. Collegium antropologicum [Internet]. 2011. [pristupljeno 08.12.2024.];35(3):957-962. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:220:483603

D. Tišlarić Medenjak, et al., "Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience", Collegium antropologicum, vol. 35, br. 3, str. 957-962, 2011. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:220:483603. [Citirano: 08.12.2024.]

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Naslov (engleski)Biochemical Screening of Fetal Aneuploidies and Neural Tube Defects by »Double-Test« in Croatia: A 10 Years’ Experience
AutorDubravka Tišlarić-Medenjak
AutorVesna Košec
AutorIvana Tonković-Đurišević
AutorIvana Zec
AutorSenka Sabolović-Rudman
AutorKrunoslav Kuna
AutorRadoslav Herman
AutorTomislav Ivičević-Bakulić
AutorHrvojka Soljačić-Vraneš
AutorNeven Tučkar
AutorDubravka Mužinić
AutorDražan Butorac
AutorIvan Bolanča
AutorAndro Košec
AutorFeodora Stipoljev
Autorova ustanova(Klinički bolnički centar Sestre milosrdnice)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ginekologija i opstetricija
Sažetak (engleski)
The aim of the study is to investigate the efficiency of the second-trimester biochemical screening, with maternal serum alpha-fetoprotein (MS-AFP) and free b-subunit of human chorionic gonadotropin (free b-hCG), during the ten-year period. The study included 11,292 of pregnant women between the 15th and 18th gestational week, who underwent screening from November 1996 to December 2006. The risk for trisomy 21 and trisomy 18 were calculated by computer software, based on a model which generated the final risk for fetal aneuploidies from the pregnant woman’s a priori age risk and the likelihood ratio of the distribution of the biochemical markers, according to the second-trimester gestation. With the cut-off value of the final risk 1:250, the detection rate for trisomy 21 was 75% (21/28). In women less than or equal to 35, the detection was 57.1% (8/14) and 92.9% (13/14) in those over 35 years, respectively. The detection rate of trisomy 18 was 50% (2/4). The results confirmed that the implementation of double-test, as non-invasive screening for fetal aneuploidies, should be accepted as a complementary method of antenatal care.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCollegium antropologicum
Brojčani podacivol. 35, br. 3, str. 957-962
p-ISSN0350-6134
e-ISSN1848-9486
URN:NBNurn:nbn:hr:220:483603
Datum objave publikacije2011
URL dokumentahttps://hrcak.srce.hr/72207
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2023-06-12 08:19:21