prikaz prve stranice dokumenta Myxopapillary Ependymoma of the Spinal Cord in Adults: a Report of Personal Series and Review of Literature
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Professional paper - Review paper
Myxopapillary Ependymoma of the Spinal Cord in Adults: a Report of Personal Series and Review of Literature
Acta clinica Croatica, 59 (2020), 2; 329-337. https://doi.org/10.20471/acc.2020.59.02.17
Omerhodžić, Ibrahim; Pojskić, Mirza; Rotim, Krešimir; Splavski, Bruno; Rasulić, Lukas; I. Arnautovic, Kenan

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Omerhodžić, I., Pojskić, M., Rotim, K., Splavski, B., Rasulić, L. & I. Arnautovic, K. (2020). Myxopapillary Ependymoma of the Spinal Cord in Adults: a Report of Personal Series and Review of Literature. Acta clinica Croatica, 59. (2), 329-337. doi: 10.20471/acc.2020.59.02.17

Omerhodžić, Ibrahim, et al. "Myxopapillary Ependymoma of the Spinal Cord in Adults: a Report of Personal Series and Review of Literature." Acta clinica Croatica, vol. 59, no. 2, 2020, pp. 329-337. https://doi.org/10.20471/acc.2020.59.02.17

Omerhodžić, Ibrahim, Mirza Pojskić, Krešimir Rotim, Bruno Splavski, Lukas Rasulić and Kenan I. Arnautovic. "Myxopapillary Ependymoma of the Spinal Cord in Adults: a Report of Personal Series and Review of Literature." Acta clinica Croatica 59, no. 2 (2020): 329-337. https://doi.org/10.20471/acc.2020.59.02.17

Omerhodžić, I., et al. (2020) 'Myxopapillary Ependymoma of the Spinal Cord in Adults: a Report of Personal Series and Review of Literature', Acta clinica Croatica, 59(2), pp. 329-337. doi: 10.20471/acc.2020.59.02.17

Omerhodžić I, Pojskić M, Rotim K, Splavski B, Rasulić L, I. Arnautovic K. Myxopapillary Ependymoma of the Spinal Cord in Adults: a Report of Personal Series and Review of Literature. Acta clinica Croatica [Internet]. 2020 [cited 2024 December 08];59(2):329-337. doi: 10.20471/acc.2020.59.02.17

I. Omerhodžić, M. Pojskić, K. Rotim, B. Splavski, L. Rasulić and K. I. Arnautovic, "Myxopapillary Ependymoma of the Spinal Cord in Adults: a Report of Personal Series and Review of Literature", Acta clinica Croatica, vol. 59, no. 2, pp. 329-337, 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:220:356449. [Accessed: 08 December 2024]

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Title (english)Myxopapillary Ependymoma of the Spinal Cord in Adults: a Report of Personal Series and Review of Literature
Title (croatian)Miksopapilarni ependimom kralježnične moždine u odraslih: prikaz osobne serije i pregled literature
AuthorIbrahim Omerhodžić https://orcid.org/0000-0001-5143-8801
AuthorMirza Pojskić
AuthorKrešimir Rotim
AuthorBruno Splavski https://orcid.org/0000-0002-4483-9364
AuthorLukas Rasulić https://orcid.org/0000-0002-5674-0425
AuthorKenan I. Arnautovic https://orcid.org/0000-0003-3745-288X
Author's institution(Sestre milosrdnice University Hospital Center)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Neurology
Abstract (english)
Myxopapillary ependymomas (MPE) of the spinal cord are slow-growing benign tumors most frequently found in adults between 30 and 50 years of age. They arise from the ependyma of the filum terminale and are located in the area of the medullary conus and cauda. The recommended treatment option is gross total resection, while patients undergoing subtotal resection usually require radiotherapy. Complete resection without capsular violation can be curative and is often accomplished by simple resection of the filum above and below the tumor mass. Nevertheless, dissemination and distant treatment failure may occur in approximately 30% of the cases. In this paper, we propose an original MPE classification, which is based upon our personal series report concerned with tumor location and its correlation with the extent of resection. We also provide literature review, discussing surgical technique, tumor recurrence rate and dissemination, and adjuvant treatment. In conclusion, our findings suggest that MPE management based on the proposed 5-type tumor classification is favorable when total surgical resection is performed in carefully selected patients. Yet, further studies on a much broader model is obligatory to confirm this.
Abstract (croatian)
Miksopapilarni ependimomi (MPE) kralježnične moždine sporo su rastući, dobroćudni tumori najčešće zastupljeni u odraslih u dobi između 30 i 50 godina života. Nastaju iz ependima filuma terminale, a pretežito su smješteni u području medularnoga konusa i kaude. Kirurško uklanjanje tumora u cijelosti preporučena je metoda liječenja, dok u bolesnika u kojih to nije moguće učiniti u obzir dolazi subtotalna resekcija nakon koje je potrebno zračenje. Potpuno uklanjanje tumora uz očuvanje cjelovitosti tumorske kapsule postiže se jednostavnom resekcijom filuma terminale iznad i ispod tumorske mase, što može dovesti do izlječenja. Unatoč tomu, tumorska diseminacija uzduž neuralne osi može se javiti u oko 30% slučajeva. U ovom radu predlažemo originalnu klasifikaciju MPE koja prosuđuje smještaj tumora i obujam tumorske resekcije, a temeljena je na osobnoj seriji operiranih bolesnika. Također raspravljamo o kirurškoj tehnici, o mogućnostima recidiva i širenja ovakvih tumora, kao i o oblicima pomoćnog liječenja, koristeći se pregledom literature. Zaključujemo kako naši rezultati zagovaraju kirurško liječenje temeljeno na predloženoj originalnoj tumorskoj klasifikaciji, koje može biti uspješno u pažljivo odabranih bolesnika u kojih je tumor uklonjen u cijelosti. Naknadna istraživanja na znatno većem uzorku potrebna su za potvrdu naših rezultata.
Keywords (english)
Keywords (croatian)
Languageenglish
Languagecroatian
Publication typeProfessional paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleActa clinica Croatica
Numberingvol. 59, no. 2, pp. 329-337
p-ISSN0353-9466
e-ISSN1333-9451
DOIhttps://doi.org/10.20471/acc.2020.59.02.17
URN:NBNurn:nbn:hr:220:356449
Publication2020
Document URLhttps://hrcak.srce.hr/243692
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2024-06-25 07:30:07