prikaz prve stranice dokumenta Surgical and Seizure Treatment Outcomes in Adult Dysembryoplastic Neuroepithelial Tumors: a Case Series
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Scientific paper - Original scientific paper
Surgical and Seizure Treatment Outcomes in Adult Dysembryoplastic Neuroepithelial Tumors: a Case Series
Acta clinica Croatica, 60. (2021), 4.; 627-630. https://doi.org/10.20471/acc.2021.60.04.09
Sajko, Tomislav; Rotim, Krešimir; Jurilj, Mia; Rotim, Ante; Splavski, Bruno; Jurčić Čulina, Ivana

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Sajko, T., Rotim, K., Jurilj, M., Rotim, A., Splavski, B. & Jurčić Čulina, I. (2021). Surgical and Seizure Treatment Outcomes in Adult Dysembryoplastic Neuroepithelial Tumors: a Case Series. Acta clinica Croatica, 60.. (4.), 627-630. doi: 10.20471/acc.2021.60.04.09

Sajko, Tomislav, et al. "Surgical and Seizure Treatment Outcomes in Adult Dysembryoplastic Neuroepithelial Tumors: a Case Series." Acta clinica Croatica, vol. 60., no. 4., 2021, pp. 627-630. https://doi.org/10.20471/acc.2021.60.04.09

Sajko, Tomislav, Krešimir Rotim, Mia Jurilj, Ante Rotim, Bruno Splavski and Ivana Jurčić Čulina. "Surgical and Seizure Treatment Outcomes in Adult Dysembryoplastic Neuroepithelial Tumors: a Case Series." Acta clinica Croatica 60., no. 4. (2021): 627-630. https://doi.org/10.20471/acc.2021.60.04.09

Sajko, T., et al. (2021) 'Surgical and Seizure Treatment Outcomes in Adult Dysembryoplastic Neuroepithelial Tumors: a Case Series', Acta clinica Croatica, 60.(4.), pp. 627-630. doi: 10.20471/acc.2021.60.04.09

Sajko T, Rotim K, Jurilj M, Rotim A, Splavski B, Jurčić Čulina I. Surgical and Seizure Treatment Outcomes in Adult Dysembryoplastic Neuroepithelial Tumors: a Case Series. Acta clinica Croatica [Internet]. 2021 [cited 2024 December 07];60.(4.):627-630. doi: 10.20471/acc.2021.60.04.09

T. Sajko, K. Rotim, M. Jurilj, A. Rotim, B. Splavski and I. Jurčić Čulina, "Surgical and Seizure Treatment Outcomes in Adult Dysembryoplastic Neuroepithelial Tumors: a Case Series", Acta clinica Croatica, vol. 60., no. 4., pp. 627-630, 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:220:165758. [Accessed: 07 December 2024]

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Metadata
Title (english)Surgical and Seizure Treatment Outcomes in Adult Dysembryoplastic Neuroepithelial Tumors: a Case Series
Title (croatian)Ishod kirurškog liječenja i epileptičnih napadaja kod disembrioplastičnih neuroepitelijskih tumora u odraslih: prikaz serije slučajeva
AuthorTomislav Sajko
AuthorKrešimir Rotim
AuthorMia Jurilj
AuthorAnte Rotim
AuthorBruno Splavski
AuthorIvana Jurčić Čulina
Author's institution(Sestre milosrdnice University Hospital Center)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Neurology
Abstract (english)
Dysembryoplastic neuroepithelial tumors (DNETs) are benign neoplasms classified in the category of glioneuronal tumors. The estimated incidence of DNETs is 0.03 per 100,000 person per year with the age peak in a range between 10 and 14 years, and decreasing dramatically with increasing age. They are seldom diagnosed in persons above 20 years of age, being a cause of tumorrelated intractable epilepsy that begins in childhood or adolescence. They have been proven to be the second most common type of epileptogenic tumors in pediatric population. These rare tumors cause chronic drug-resistant partial complex seizures with or without secondary generalization. Herein, we provide institutional case series of six adult patients with temporal lobe DNET presenting with complex partial seizures. Lesionectomy was performed with tumor resection in toto in three patients. In another three, partial resection was performed, whereas tumor remnant was left intact to avoid possible basal ganglia damage. All patients were seizure free postoperatively. Lesionectomy alone in temporal lobe epilepsy was associated with less favorable outcome than anterior temporal lobectomy. Total tumor removal is considered a major prognostic factor in most studies.
Abstract (croatian)
Disembrioplastični neuroepitelijski tumori (DNET) dobroćudne su novotvorine koje se svrstavaju u skupinu glioneuralnih tumora. Njihova je godišnja učestalost 0,03 na 100.000 stanovnika s vrškom pojavnosti u dobi između 10 i 14 godina života. Učestalost se smanjuje s porastom dobi, a tumori se rijetko javljaju nakon 20. godine života. Dokazani su kao uzrok epilepsije koja započinje u djetinjstvu i adolescenciji te kao drugi najčešći tip tumora koji uzrokuje epileptične napadaje u dječjoj dobi. Ovi rijetki tumori uzrokuju kronične i na terapiju otporne parcijalne složene epileptične napadaje s generalizacijom ili bez nje. U ovom radu prikazujemo institucijsku seriju šest odraslih bolesnika s DNET-om u području temporalnog režnja koji su se prezentirali složenim parcijalnim epileptičnim napadajima. Tri su bolesnika kirurški liječena lezionektomijom s totalnom resekcijom tumora. U preostala tri bolesnika učinjena je parcijalna resekcija, a dio tumora je ostavljen kako bi se izbjeglo oštećenje bazalnih ganglija. Svi su bolesnici nakon zahvata bili bez epileptičnih napadaja. U slučaju temporalne epilepsije, a u usporedbi s prednjom temporalnom lobektomijom, selektivno uklanjanje tumorske lezije bilo je povezano s lošijim ishodom liječenja. Uklanjanje tumora u cijelosti smatra se važnim prognostičkim pokazateljem ishoda liječenja u većini provedenih istraživanja.
Keywords (english)
Keywords (croatian)
Languageenglish
Languagecroatian
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleActa clinica Croatica
Numberingvol. 60., no. 4., pp. 627-630
p-ISSN0353-9466
e-ISSN1333-9451
DOIhttps://doi.org/10.20471/acc.2021.60.04.09
URN:NBNurn:nbn:hr:220:165758
Publication2021
Document URLhttps://hrcak.srce.hr/275494
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2024-06-24 08:29:53