prikaz prve stranice dokumenta Validating the predictive ability of the 2MACE score for major adverse cardiovascular events in patients with atrial fibrillation: results from phase II/III of the GLORIA-AF registry
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Validating the predictive ability of the 2MACE score for major adverse cardiovascular events in patients with atrial fibrillation: results from phase II/III of the GLORIA-AF registry
Journal of Thrombosis and Thrombolysis, 57 (2023), 1; 39-49. https://doi.org/10.1007/s11239-023-02866-y
Ding, Wern Yew; ...; Kes, Vanja Basic; Kalan, Marica Bracic; Brkljacic, Diana Delic; Knezevic, Aleksandar; Kovacic, Dragan; Nazlić, Jurica; Persic, Viktor; Pivac, Nediljko; Poljakovic, Zdravka

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Ding, W. Y., Kes, V. B., Kalan, M. B., Brkljacic, D. D., Knezevic, A., Kovacic, D. ... Poljakovic, Z. (2023). Validating the predictive ability of the 2MACE score for major adverse cardiovascular events in patients with atrial fibrillation: results from phase II/III of the GLORIA-AF registry. Journal of Thrombosis and Thrombolysis, 57. (1), 39-49. doi: 10.1007/s11239-023-02866-y

Ding, Wern Yew, et al. "Validating the predictive ability of the 2MACE score for major adverse cardiovascular events in patients with atrial fibrillation: results from phase II/III of the GLORIA-AF registry." Journal of Thrombosis and Thrombolysis, vol. 57, br. 1, 2023, str. 39-49. https://doi.org/10.1007/s11239-023-02866-y

Ding, Wern Yew, Vanja Basic Kes, Marica Bracic Kalan, Diana Delic Brkljacic, Aleksandar Knezevic, Dragan Kovacic, Jurica Nazlić, Viktor Persic, Nediljko Pivac i Zdravka Poljakovic. "Validating the predictive ability of the 2MACE score for major adverse cardiovascular events in patients with atrial fibrillation: results from phase II/III of the GLORIA-AF registry." Journal of Thrombosis and Thrombolysis 57, br. 1 (2023): 39-49. https://doi.org/10.1007/s11239-023-02866-y

Ding, W. Y., et al. (2023) 'Validating the predictive ability of the 2MACE score for major adverse cardiovascular events in patients with atrial fibrillation: results from phase II/III of the GLORIA-AF registry', Journal of Thrombosis and Thrombolysis, 57(1), str. 39-49. doi: 10.1007/s11239-023-02866-y

Ding WY, Kes VB, Kalan MB, Brkljacic DD, Knezevic A, Kovacic D, i sur.. Validating the predictive ability of the 2MACE score for major adverse cardiovascular events in patients with atrial fibrillation: results from phase II/III of the GLORIA-AF registry. Journal of Thrombosis and Thrombolysis [Internet]. 11.08.2023. [pristupljeno 18.11.2024.];57(1):39-49. doi: 10.1007/s11239-023-02866-y

W. Y. Ding, et al., "Validating the predictive ability of the 2MACE score for major adverse cardiovascular events in patients with atrial fibrillation: results from phase II/III of the GLORIA-AF registry", Journal of Thrombosis and Thrombolysis, vol. 57, br. 1, str. 39-49, Kolovoz 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:220:023108. [Citirano: 18.11.2024.]

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Naslov (engleski)Validating the predictive ability of the 2MACE score for major adverse cardiovascular events in patients with atrial fibrillation: results from phase II/III of the GLORIA-AF registry
AutorWern Yew Ding
Autor
...
AutorVanja Basic Kes
AutorMarica Bracic Kalan
AutorDiana Delic Brkljacic
AutorAleksandar Knezevic
AutorDragan Kovacic
AutorJurica Nazlić
AutorViktor Persic
AutorNediljko Pivac
AutorZdravka Poljakovic
Autorova ustanova(Klinički bolnički centar Sestre milosrdnice)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
The 2MACE score was specifically developed as a risk-stratifcation tool in atrial fibrillation (AF) to predict cardiovascular outcomes. We evaluated the predictive ability of the 2MACE score in the GLORIA-AF registry. All eligible patients from phase II/III of the prospective global GLORIA-AF registry were included. Major adverse cardiac events (MACEs) were defned as the composite outcome of stroke, myocardial infarction and cardiovascular death. Cox proportional hazards were used to examine the relationship between the 2MACE score and study outcomes. Predictive capability of the 2MACE score was investigated using receiver-operating characteristic curves. A total of 25,696 patients were included (mean age 71 years, female 44.9%). Over 3 years, 1583 MACEs were recorded. Patients who had MACE were older, with more cardiovascular risk factors and were less likely to be managed using a rhythm-control strategy. The median 2MACE score in the MACE and non-MACE groups were 2 (IQR 1–3) and 1 (IQR 0–2), respectively (p<0.001). The 2MACE score was positively associated with an increase in the risk of MACE, with a score of ≥2 providing the best combination of sensitivity (69.6%) and specificity (51.6%), HR 2.47 (95% CI, 2.21–2.77). The 2MACE score had modest predictive performance for MACE in patients with AF (AUC 0.655 (95% CI, 0.641–0.669)). Our analysis in this prospective global registry demonstrates that the 2MACE score can adequately predict the risk of MACE (defined as myocardial infarction, CV death and stroke) in patients with AF.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Thrombosis and Thrombolysis
Brojčani podacivol. 57, br. 1, str. 39-49
e-ISSN1573-742X
DOIhttps://doi.org/10.1007/s11239-023-02866-y
URN:NBNurn:nbn:hr:220:023108
Datum objave publikacije2023-08-11
URL dokumentahttps://link.springer.com/10.1007/s11239-023-02866-y
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
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Datum i vrijeme pohrane2024-06-17 10:04:05