prikaz prve stranice dokumenta Anticancer and Antioxidative Effects of Micronized Zeolite Clinoptilolite
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Anticancer and Antioxidative Effects of Micronized Zeolite Clinoptilolite
Anticancer Research, 23 (2003), 2B; 1589-1595. urn:nbn:hr:220:890987
Žarković, Neven; Žarković, Kamelija; Kralj, Marijeta; Borović, Suzana; Sabolović, Senka; Poljak-Blaži, Marija; Čipak, Ana; Pavelić, Krešimir

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Žarković, N., Žarković, K., Kralj, M., Borović, S., Sabolović, S., Poljak Blaži, M. ... Pavelić, K. (2003). Anticancer and Antioxidative Effects of Micronized Zeolite Clinoptilolite. Anticancer Research, 23. (2B), 1589-1595. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:220:890987

Žarković, Neven, et al. "Anticancer and Antioxidative Effects of Micronized Zeolite Clinoptilolite." Anticancer Research, vol. 23, br. 2B, 2003, str. 1589-1595. https://urn.nsk.hr/urn:nbn:hr:220:890987

Žarković, Neven, Kamelija Žarković, Marijeta Kralj, Suzana Borović, Senka Sabolović, Marija Poljak Blaži, Ana Čipak i Krešimir Pavelić. "Anticancer and Antioxidative Effects of Micronized Zeolite Clinoptilolite." Anticancer Research 23, br. 2B (2003): 1589-1595. https://urn.nsk.hr/urn:nbn:hr:220:890987

Žarković, N., et al. (2003) 'Anticancer and Antioxidative Effects of Micronized Zeolite Clinoptilolite', Anticancer Research, 23(2B), str. 1589-1595. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:220:890987 (Datum pristupa: 09.12.2024.)

Žarković N, Žarković K, Kralj M, Borović S, Sabolović S, Poljak Blaži M, i sur.. Anticancer and Antioxidative Effects of Micronized Zeolite Clinoptilolite. Anticancer Research [Internet]. 2003. [pristupljeno 09.12.2024.];23(2B):1589-1595. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:220:890987

N. Žarković, et al., "Anticancer and Antioxidative Effects of Micronized Zeolite Clinoptilolite", Anticancer Research, vol. 23, br. 2B, str. 1589-1595, 2003. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:220:890987. [Citirano: 09.12.2024.]

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Podaci o radu
Naslov (engleski)Anticancer and Antioxidative Effects of Micronized Zeolite Clinoptilolite
AutorNeven Žarković
AutorKamelija Žarković
AutorMarijeta Kralj
AutorSuzana Borović
AutorSenka Sabolović
AutorMarija Poljak-Blaži
AutorAna Čipak
AutorKrešimir Pavelić
Autorova ustanova(Klinički bolnički centar Sestre milosrdnice)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Background: Treatment of cancer-bearing mice and dogs with micronized zeolite clinoptilolite (MZ) led to improvement of the overall health status, prolongation of life span and decrease of tumor size in some cases. It also reduced lipid peroxidation in the liver of mice. Materials and Methods: The experiments were performed on various tumor cell cultures and tumor-bearing animals. Immunohistochemistry was used to analyze if MZ could interfere with Doxorubicin-induced lipid peroxidation and consequential production of 4-hydroxynonenal (HNE). Results: MZ reduced the metabolic rate of cancer cells and increased binding of HNE to albumin in vitro. It selectively reduced generation of HNE in vivo in tumor stroma after Doxorubicin treatment leaving onset of lipid peroxidation intact in malignant cells. Combined treatment with Doxorubicin and MZ resulted in strong reduction of the pulmonary metastasis count increasing anticancer effects of Doxorubicin. Conclusion: Interference of MZ with lipid peroxidation might explain some of the beneficial effects of this particular zeolite in combined cancer therapy.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaAnticancer Research
Brojčani podacivol. 23, br. 2B, str. 1589-1595
p-ISSN0250-7005
e-ISSN1791-7530
URN:NBNurn:nbn:hr:220:890987
Datum objave publikacije2003
Vrsta resursaTekst
Prava pristupaInstitucijski pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-10-18 10:36:23