prikaz prve stranice dokumenta Long-Term Outcome of Differentiated Thyroid Cancer Patients—Fifty Years of Croatian Thyroid Disease Referral Centre Experience
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Long-Term Outcome of Differentiated Thyroid Cancer Patients—Fifty Years of Croatian Thyroid Disease Referral Centre Experience
Diagnostics, 12 (2022), 4; 866. https://doi.org/10.3390/diagnostics12040866
Jukić, Tomislav; Blažeković, Ivan; Franceschi, Maja; Petranović Ovčariček, Petra; Bosak Butković, Marija; Dabelić, Nina; Granić, Roko; Punda, Marija; Sonicki, Zdenko; Vagić, Davor; Fröbe, Ana; Kusić, Zvonko

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Jukić, T., Blažeković, I., Franceschi, M., Petranović Ovčariček, P., Bosak Butković, M., Dabelić, N. ... Kusić, Z. (2022). Long-Term Outcome of Differentiated Thyroid Cancer Patients—Fifty Years of Croatian Thyroid Disease Referral Centre Experience. Diagnostics, 12. (4). doi: 10.3390/diagnostics12040866

Jukić, Tomislav, et al. "Long-Term Outcome of Differentiated Thyroid Cancer Patients—Fifty Years of Croatian Thyroid Disease Referral Centre Experience." Diagnostics, vol. 12, br. 4, 2022. https://doi.org/10.3390/diagnostics12040866

Jukić, Tomislav, Ivan Blažeković, Maja Franceschi, Petra Petranović Ovčariček, Marija Bosak Butković, Nina Dabelić, Roko Granić, et al. "Long-Term Outcome of Differentiated Thyroid Cancer Patients—Fifty Years of Croatian Thyroid Disease Referral Centre Experience." Diagnostics 12, br. 4 (2022). https://doi.org/10.3390/diagnostics12040866

Jukić, T., et al. (2022) 'Long-Term Outcome of Differentiated Thyroid Cancer Patients—Fifty Years of Croatian Thyroid Disease Referral Centre Experience', Diagnostics, 12(4). doi: 10.3390/diagnostics12040866

Jukić T, Blažeković I, Franceschi M, Petranović Ovčariček P, Bosak Butković M, Dabelić N, i sur.. Long-Term Outcome of Differentiated Thyroid Cancer Patients—Fifty Years of Croatian Thyroid Disease Referral Centre Experience. Diagnostics [Internet]. 2022. [pristupljeno 08.12.2024.];12(4). doi: 10.3390/diagnostics12040866

T. Jukić, et al., "Long-Term Outcome of Differentiated Thyroid Cancer Patients—Fifty Years of Croatian Thyroid Disease Referral Centre Experience", Diagnostics, vol. 12, br. 4, 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:220:541917. [Citirano: 08.12.2024.]

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Podaci o radu
Naslov (engleski)Long-Term Outcome of Differentiated Thyroid Cancer Patients—Fifty Years of Croatian Thyroid Disease Referral Centre Experience
AutorTomislav Jukić
AutorIvan Blažeković
AutorMaja Franceschi
AutorPetra Petranović Ovčariček
AutorMarija Bosak Butković
AutorNina Dabelić
AutorRoko Granić
AutorMarija Punda
AutorZdenko Sonicki
AutorDavor Vagić
AutorAna Fröbe
AutorZvonko Kusić
Autorova ustanova(Klinički bolnički centar Sestre milosrdnice)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Onkologija
Sažetak (engleski)
Background: Indolent nature but a high incidence of differentiated thyroid cancer (DTC) remains a challenge for optimizing patient care. Therefore, prognostic factors present valuable information for determining an adequate clinical approach. Methods: This study assessed prognostic features of 1167 papillary (PTC) and 215 follicular (FTC) thyroid cancer patients that had undergone surgery between 1962 and 2012, and were followed-up up to 50 years in a single institution, till April 2020. Age, gender, tumor size, presence of local and distant metastases at presentation, extrathyroidal extension, disease recurrence, and cancer-specific survival were evaluated. Results: In multivariate analysis, factors affecting the worse outcome were age (p = 0.005), tumor size (p = 0.006), and distant metastases (p = 0.001) in PTC, while extrathyroidal extension (p < 0.001), neck recurrence (p = 0.002), and distant metastases (p < 0.001) in FTC patients. Loco-regional recurrence rate was 6% for PTC and 4.7% for FTC patients, while distant metastases were detected in 4.2% PTC and 14.4% of FTC patients. The 10-year cancer-specific survival rates for PTC and FTC were 98.6% and 89.8%, respectively (p < 0.001). Conclusions: Negative prognostic factors, besides distant metastases, were older age and greater tumor size in PTC, and extrathyroidal extension and neck recurrence in FTC patients. The recurrence and mortality rates were very low.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaDiagnostics
Brojčani podacivol. 12, br. 4, 866
e-ISSN2075-4418
DOIhttps://doi.org/10.3390/diagnostics12040866
URN:NBNurn:nbn:hr:220:541917
Datum objave publikacije2022
URL dokumentahttps://www.mdpi.com/2075-4418/12/4/866
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-01-05 09:58:24