prikaz prve stranice dokumenta Proofs for implementation of higher HE4 and ROMA index cut-off values in ovarian cancer preoperative stratification
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Proofs for implementation of higher HE4 and ROMA index cut-off values in ovarian cancer preoperative stratification
Journal of Obstetrics and Gynaecology, 39 (2019), 2; 195-201. https://doi.org/10.1080/01443615.2018.1476471
Špacir Prskalo, Zvjezdana; Bulić, Petra; Langer, Sanja; Gaće, Mihaela; Puljiz, Mario; Danolić, Damir; Alvir, Ilija; Mamić, Ivica; Šušnjar, Lucija; Mayer, Ljiljana

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Špacir Prskalo, Z., Bulić, P., Langer, S., Gaće, M., Puljiz, M., Danolić, D. ... Mayer, Lj. (2019). Proofs for implementation of higher HE4 and ROMA index cut-off values in ovarian cancer preoperative stratification. Journal of Obstetrics and Gynaecology, 39. (2), 195-201. doi: 10.1080/01443615.2018.1476471

Špacir Prskalo, Zvjezdana, et al. "Proofs for implementation of higher HE4 and ROMA index cut-off values in ovarian cancer preoperative stratification." Journal of Obstetrics and Gynaecology, vol. 39, br. 2, 2019, str. 195-201. https://doi.org/10.1080/01443615.2018.1476471

Špacir Prskalo, Zvjezdana, Petra Bulić, Sanja Langer, Mihaela Gaće, Mario Puljiz, Damir Danolić, Ilija Alvir, Ivica Mamić, Lucija Šušnjar i Ljiljana Mayer. "Proofs for implementation of higher HE4 and ROMA index cut-off values in ovarian cancer preoperative stratification." Journal of Obstetrics and Gynaecology 39, br. 2 (2019): 195-201. https://doi.org/10.1080/01443615.2018.1476471

Špacir Prskalo, Z., et al. (2019) 'Proofs for implementation of higher HE4 and ROMA index cut-off values in ovarian cancer preoperative stratification', Journal of Obstetrics and Gynaecology, 39(2), str. 195-201. doi: 10.1080/01443615.2018.1476471

Špacir Prskalo Z, Bulić P, Langer S, Gaće M, Puljiz M, Danolić D, i sur.. Proofs for implementation of higher HE4 and ROMA index cut-off values in ovarian cancer preoperative stratification. Journal of Obstetrics and Gynaecology [Internet]. 2019. [pristupljeno 08.12.2024.];39(2):195-201. doi: 10.1080/01443615.2018.1476471

Z. Špacir Prskalo, et al., "Proofs for implementation of higher HE4 and ROMA index cut-off values in ovarian cancer preoperative stratification", Journal of Obstetrics and Gynaecology, vol. 39, br. 2, str. 195-201, 2019. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:220:355695. [Citirano: 08.12.2024.]

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Naslov (engleski)Proofs for implementation of higher HE4 and ROMA index cut-off values in ovarian cancer preoperative stratification
AutorZvjezdana Špacir Prskalo
AutorPetra Bulić
AutorSanja Langer
AutorMihaela Gaće
AutorMario Puljiz
AutorDamir Danolić
AutorIlija Alvir
AutorIvica Mamić
AutorLucija Šušnjar
AutorLjiljana Mayer
Autorova ustanova(Klinički bolnički centar Sestre milosrdnice)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ginekologija i opstetricija
Sažetak (engleski)
This study aimed to identify and quantify the clinical significance of the HE4 and ROMA index in patients with an adnexal tumour. We recruited 159 women and the HE4 and CA125 were measured with an electrochemiluminescence immunoassay in the sera. We used the Kolmogorov–Smirnov test, Mann–Whitney’s test and logistic regression to interpret the data. In the premenopausal group (n = 57), the ROC analysis (with cut-off: 86.1 pmol/L for HE4; 40.7 U/L for CA125 and 21.9% for ROMA) demonstrated the superior prognostic potential of those markers when the higher cut-offs used are compared to producers. The AUC for HE4/CA125/ROMA were 0.846/0.867/0.846, respectively. The HE4/ROMA showed 85.7% sensitivity and 94% specificity. In the postmenopausal group (n = 102), the ROC analysis cut-off values were: 99.8 pmol/L for HE4; 45.8 U/L for CA125 and 38.4% for ROMA. AUC for HE4/CA125/ROMA were 0.928/0.899/0.927, respectively. HE4 had an 86.1% sensitivity at 92.4% specificity, while ROMA showed an 88.9% sensitivity at a 90.9% specificity.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeNepoznato
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Obstetrics and Gynaecology
Brojčani podacivol. 39, br. 2, str. 195-201
p-ISSN0144-3615
e-ISSN1364-6893
DOIhttps://doi.org/10.1080/01443615.2018.1476471
URN:NBNurn:nbn:hr:220:355695
Datum objave publikacije2019
URL dokumentahttps://www.tandfonline.com/doi/full/10.1080/01443615.2018.1476471
Vrsta resursaTekst
Prava pristupaInstitucijski pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-06-10 10:06:06